I have a new 20 with 96 hrs. since May. Most of my flying is on business and I regularly fly from upstate NY to Madison, WI, Chicago and Milwaukee as a few examples. I came back from Madison yesterday at 13,000 feet and ran a comparison of fuel burn and speed to see if I really want to go up to a 22. This is what I found using book figures at 12,000 (my 20 regularly makes book), fuel burn in the 20 at max power and RPM 51.47 gal/4.81 hrs. The 22 would burn 70.12 gal and take 4.19 hours. Total time 22 beats the 20 by 37 minutes at an additional cost of 55.51 (using 3) or $1.50 per minute of flight. Now figure in the 45-62 thousand dollars difference in price, the lower TBO and the increase in insurance, etc. In my opinion unless you need the 4 seats full or live in a high altitude area the 20 presents a very attractive package. If you are independantly wealthy and don’t need to fill the seats or live in a high altitude airport, then go for it as money is no object. Bye the way I actually flew back non-stop from Madison, WI to my home base at Glens Falls, NY non-stop at 13,000ft. running 2500RPM, 50 degrees lean of peak and still have 1:35 minutes of fuel left in the tanks. Total time was 4hrs 38 min. for a 760NM trip. Of course I had about a 10-14 knot tail wind component. My fuel burn at 50 degrees LOP was 6.9GPH. Hope this helps those of you struggling with the choice.